Papers in Scientific Journals (41)
Silva S. S., Rodrigues, L.C., Fernandes E. M., Gomes J. M., Vilas-Boas A., Pirraco R. P., and Reis R. L.,
"Approach on chitosan/virgin coconut oil-based emulsion matrices as a platform to design superabsorbent materials",
Carbohydrate polymers , vol. 249, pp. 116839, doi:
10.1016/j.carbpol.2020.116839, 2020.
Carvalho D. N., López-Cebral R., Sousa R. O., Alves A. L., Silva S. S., Oliveira J. M., Reys L. L., Reis R. L., and Silva T. H.,
"Marine collagen-chitosan-fucoidan cryogels as cell-laden biocomposites envisaging tissue engineering",
Biomedical Materials, vol. 15, issue 5, pp. 055030, doi:
10.1088/1748-605X/ab9f04, 2020.
Gonçalves C., Silva S. S., Gomes J. M., Oliveira I. M., Canadas R. F., Maia F. R., Radhouani H., Reis R. L., and Oliveira J. M.,
"Ionic liquid-mediated processing of SAIB-Chitin scaffolds",
Acs Sustainable Chemistry & Engineering, vol. 8, issue 9, pp. 3986-3994, doi:
10.1021/acssuschemeng.0c00385, 2020.
Silva J. M., Rodrigues, L.C., Silva S. S., Reis R. L., and Duarte A. R. C.,
"Engineered tubular structures based on chitosan for tissue engineering applications",
Journal of Biomaterials Applications, pp. 1-12, doi:
10.1177/0885328217744698, 2017.
Reys L. L., Silva S. S., Pirraco R. P., Marques A. P., Mano J. F., Silva T. H., and Reis R. L.,
"Influence of freezing temperature and deacetylation degree on the performance of freeze-dried chitosan scaffolds towards cartilage tissue engineering",
European Polymer Journal, vol. 95, issue C, pp. 232-240, doi:
10.1016/j.eurpolymj.2017.08.017, 2017.
Reys L. L., Silva S. S., Soares da Costa D., Oliveira N. M., Mano J. F., Reis R. L., and Silva T. H.,
"Fucoidan hydrogels photo-cross-linked with visible radiation as matrices for cell culture",
ACS Biomaterials Science & Engineering, vol. 2, issue 7, pp. 1151–1161, doi:
10.1021/acsbiomaterials.6b00180, 2016.
Silva S. S., Oliveira N. M., Oliveira, M.B., Soares da Costa D., Naskar D., Mano J. F., Kundu S. C., and Reis R. L.,
"Fabrication and characterization of Eri silk fibers-based sponges for biomedical application",
Acta Biomaterialia, vol. 32, pp. 178-189, doi:
10.1016/j.actbio.2016.01.003, 2016.
Silva S. S., Duarte A. R. C., Oliveira J. M., Mano J. F., and Reis R. L.,
"Alternative methodology for chitin/hydroxyapatite composites using ionic liquids and supercritical fluid technology",
Journal of Bioactive and Compatible Polymers, vol. 28, issue 5, pp. 481-491, doi:
10.1177/0883911513501595, 2013.
Silva S. S., Popa E. G., Gomes M. E., Oliveira M. B., Nayak S., Bano S., Mano J. F., Kundu S. C., and Reis R. L.,
"Silk hydrogels from non-mulberry and mulberry silkworm cocoons processed with ionic liquids",
Acta Biomaterialia, vol. 9, issue 11, pp. 8972-8982, doi:
10.1016/j.actbio.2013.06.044, 2013.
Silva S. S., Caridade S. G., Mano J. F., and Reis R. L.,
"Effect of crosslinking in chitosan/aloe vera-based membranes for biomedical applications",
Carbohydrate Polymers, 1, vol. 98, pp. 581-588, doi:
10.1016/j.carbpol.2013.06.022, 2013.
Reys L. L., Silva S. S., Oliveira J. M., Caridade S. G., Mano J. F., Silva T. H., and Reis R. L.,
"Revealing the potential of squid chitosan-based structures for biomedical applications",
Biomedical Materials, vol. 8, issue 4, doi:
doi:10.1088/1748-6041/8/4/045002, 2013.
Santos T. C., Hoering B., Reise K., Marques A. P., Silva S. S., Oliveira J. M., Mano J. F., Castro A. G., Reis R. L., and van Griensven M.,
"In vivo performance of chitosan/soy-based membranes as wound dressing devices for acute skin wounds",
Tissue Engineering-A, vol. 19, issue 7-8, pp. 860-870, doi:
10.1089/ten.TEA.2011.0651, 2013.
Silva S. S., Popa E. G., Gomes M. E., Cerqueira M. T., Marques A. P., Caridade S. G., Teixeira P., Sousa C., Mano J. F., and Reis R. L.,
"An investigation of the potential application of chitosan/aloe-based membranes for regenerative medicine",
Acta Biomaterialia , doi:
10.1016/j.actbio.2013.02.027, 2013.
Duarte A. R. C., Santo V. E., Alves A., Silva S. S., Moreira-Silva J., Silva T. H., Marques A. P., Gomes M. E., Sousa R. A., Mano J. F., and Reis R. L.,
"Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine",
The Journal of Supercritical Fluids, vol. 79, pp. 177-185, doi:
10.1016/j.supflu.2013.01.004, 2013.
Silva S. S., Santos T. C., Cerqueira M. T., Marques A. P., Reys L. L., Silva T. H., Caridade S. G., Mano J. F., and Reis R. L.,
"The use of ionic liquids in the processing of chitosan/silk hydrogels for biomedical applications",
Green Chemistry , vol. 14, pp. 1463-1470, doi:
10.1039/C2GC16535J, 2012.
Reys L. L., Silva S. S., Oliveira J. M., Frias A. M., Mano J. F., Silva T. H., and Reis R. L.,
"Valorization of chitosan from squid pens and further use on the development of scaffolds for biomedicalapplications",
The International Journal of Artificial Organs, vol. 34, issue 8, pp. 704, 2012.
Oliveira J. M., Sousa R. A., Malafaya P. B., Silva S. S., Hirose M., Ohgushi H., Mano J. F., and Reis R. L.,
"In vivo study of dendron-like nanoparticles for stem cells tune-up: From nano to tissues",
Nanomedicine: Nanotechnology, Biology, and Medicine, vol. 7, pp. 914–924, doi:
10.1016/j.nano.2011.03.002, 2011.
Santos T. C., Marques A. P., Silva S. S., Oliveira J. M., Mano J. F., Castro A. G., van Griensven M., and Reis R. L.,
"Chitosan improves the biological performance of soy-based biomaterials",
Tissue Engineering, vol. 16, issue 9, pp. 2883-2890, 2010.
Oliveira J. M., Silva S. S., Malafaya P. B., Rodrigues M. T., Kotokuki N., Hirose M., Gomes M. E., Mano J. F., Ohgushi H., and Reis R. L.,
"Macroporous hydroxyapatite scaffolds for bone tissue engineering applications: Physicochemical characterization and assessment of rat bone marrow stromal cells viability",
Journal of Biomedical Materials Research: Part A, vol. 91, issue 1, pp. 175-186, 2009.
Oliveira J. M., Malafaya P. B., Silva S. S., Kotobuki N., Hirose M., Sousa R. A., Ohgushi H., Mano J. F., and Reis R. L.,
"Carboxymethylchitosan/poly(amidoamine) dendrimer nanoparticles as an intracellular delivery system of dexamethasone for inducing stem cells osteogenic differentiation and de novo bone formation",
Tissue Engineering and Regenerative Medicine, vol. 6, issue 12, pp. S252, 2009.
Silva S. S., Motta A., Rodrigues M. T., Pinheiro A. F. M., Gomes M. E., Mano J. F., Reis R. L., and Migliaresi C.,
"Novel Genipin Cross-linked Chitosan-Silk Fibroin Sponges for Cartilage Engineering Strategies",
Biomacromolecules , vol. 9, pp. 2764–2774, 2008.
Silva S. S., Luna S. M., Gomes M. E., Benesch J., Pashkuleva I., Mano J. F., and Reis R. L.,
"Plasma Surface Modification of Chitosan Membranes: Characterization and Preliminary Cell Response Studies ",
Macromolecular Bioscience, vol. 8, pp. 568-576, 2008.
Santos T. C., Marques A. P., Silva S. S., Oliveira J. M., Mano J. F., Castro A. G., and Reis R. L.,
"In vitro evaluation of the behaviour of human polymorphonuclear neutrophils in direct contact with chitosan-based membranes",
Journal of Biotechnology, vol. 132, issue 2, pp. 218-226, 2007.
Silva S. S., Maniglio D., Motta A., Mano J. F., Reis R. L., and Migliaresi C.,
"Genipin Modified Silk Fibroin Nanometric-Nets",
Macromolecular Bioscience, vol. 8, issue 8, pp. 766-774, 2007.
Silva S. S., Goodfellow B. J., Benesch J., Rocha J., Mano J. F., and Reis R. L.,
"Morphology and miscibility of chitosan/soy protein blended membranes",
Carbohydrate polymers, vol. 70, pp. 25-31, 2007.
Silva S. S., Ferreira R. A., Fu L., Carlos L. D., Mano J. F., Reis R. L., and Rocha J.,
"Functional nanostructured chitosan–siloxane hybrids",
JOurnal of materials chemistry, vol. 15, pp. 3952-3961, doi:
10.1039/B505875A , 2007.
Oliveira J. M., Rodrigues M. T., Silva S. S., Malafaya P. B., Gomes M. E., Viegas C. A. A., Azevedo J. T., Dias I. R., Mano J. F., and Reis R. L.,
"Novel hydroxyapatite/chitosan bilayered scaffold for osteochondral tissue-engineering applications: scaffold design and its performance when seeded with goat bone marrow stromal cells",
Biomaterials, vol. 27, pp. 6123-6137, 2006.
Silva S. S., Ferreira R. A., Fu L., Carlos L. D., Mano J. F., Reis R. L., and Rocha J.,
"Functional nanostructured chitosan-siloxane hybrids",
Journal of Materials Chemistry, vol. 15, issue 35-36, pp. 3952-3961, 2005.
Book Chapter (11)
Reys L. L., Silva S. S., Oliveira C., López-Cebral R., Neves N. M., Martins A., Oliveira J. M., Silva T. H., and Reis R. L.,
"Marine-origin Polysaccharides for Tissue Engineering and Regenrative Medicine, Chitosan and Fucoidan as illustrative examples"",
Encyclopedia of Marine Biotechnology,
Eds. Kim S. - K.,
Wiley, vol. IV, pp. 2619-2650, doi:
https://doi.org/10.1002/9781119143802.ch118, 2020.
Silva S. S., Gomes J. M., Rodrigues L. C., and Reis R. L.,
"Biomedical exploitation of chitin and chitosan-based matrices via ionic liquid processing",
Handbook of Chitin and Chitosan,
Eds. Sreerag G., Sabu T., and Anitha P.,
Elsevier, vol. 3, pp. 471-497, doi:
10.1016/B978-0-12-817966-6.00015-7, 2020.
Silva S. S., Rodrigues, L.C., Fernandes E. M., and Reis R. L.,
"Biopolymer membranes in tissue engineering",
Biopolymer Membranes and Films: Health, Food, Environment, and Energy Applications,
Eds. de Moraes M. A., da Silva C. F., and Vieira R. S.,
Elsevier, pp. 141-163, doi:
10.1016/B978-0-12-818134-8.00006-7, 2020.
Silva S. S., Rodrigues L. C., Fernandes E. M., and Reis R. L.,
"Fundamentals on biopolymers and global demand",
Biopolymer Membranes and Films,
Eds. de Moraes M. A., da Silva C. F., and Vieira R. S.,
Elsevier , 1, pp. 3-34, 2020.
Duarte A. R. C., Silva S. S., and Reis R. L.,
"Chitin/Chitosan Based Aerogels: Processing and Morphology",
Biobased Aerogels: Polysaccharide and Protein-based Materials ,
Eds. Thomas S., Pothan L. A., and Mavelil-Sam R.,
The Royal Society of Chemistry, pp. 9-24, doi:
10.1039/9781782629979-00009, 2018.
Silva S. S., Fernandes E. M., Pina S., Silva-Correia J., Vieira S., Oliveira J. M., and Reis R. L.,
"Natural-Origin Materials for Tissue Engineering and Regenerative Medicine",
Comprehensive Biomaterials II,
Eds. Ducheyne P., Healy K. E., Hutmacher D. E., Grainger D. W., and Kirkpatrick C. J.,
Elsevier, 2, pp. 228-252, doi:
10.1016/B978-0-12-803581-8.10134-1, 2017.
Reys L. L., Oliveira C., Oliveira J. M., López-Cebral R., Silva S. S., Silva T. H., and Reis R. L.,
"Polissacarídeos de origem marinha para aplicação em estratégias de engenharia de tecidos",
Valorização dos Recursos Marinhos: Biomateriais em Regeneração de Tecidos e Libertação de Fármacos,
Eds. Carmen G. S., Pilar S. P., Julio M. L., José V. A., Ricardo P. M. I., Tiago S. H., and Reis R. L.,
IIM-CSIC, Vigo, Espanha, pp. 107-145, 2015.
Silva S. S., Oliveira J. M., Sá-Lima H., Sousa R. A., Mano J. F., and Reis R. L.,
"2.211 - Polymers of Biological Origin",
Comprehensive Biomaterials,
Eds. Ducheyne P.,
Ducheyne P ,
Oxford, pp. 187-205, 2011.
Gomes M. E., Azevedo H. S., Malafaya P. B., Silva S. S., Oliveira J. M., Silva G. A., Sousa R. A., Mano J. F., and Reis R. L.,
"Natural Polymers in tissue engineering applications",
Textbook on tissue engineering,
Eds. van Blitterswijk C.,
Elsevier,
Amsterdam, 2007.
Review Paper (6)
Ramos N., Miranda M. S., Franco A. R., Silva S. S., Azevedo J., Dias I. R., Reis R. L., Viegas C., and Gomes M. E.,
"Toward Spinning Greener Advanced Silk Fibers by Feeding Silkworms with Nanomaterials",
ACS Sustainable Chemistry & Engineering, vol. 8, issue 32, pp. 11872–11887, doi:
10.1021/acssuschemeng.0c03874, 2020.
Invited Journal Paper (1)
Silva S. S., Gomes J. M., Vale A. C., Lu S., Reis R. L., and Kundu S. C.,
"Green Pathway for Processing Non-mulberry Antheraea pernyi Silk Fibroin/Chitin-Based Sponges: Biophysical and Biochemical Characterization",
Frontiers in Materials, vol. 7, pp. 1-9, doi:
10.3389/fmats.2020.00135, 2020.
Review Paper (6)
Silva T. H., Alves A., Popa E. G., Reys L. L., Gomes M. E., Sousa R. A., Silva S. S., Mano J. F., and Reis R. L.,
"Marine Algae Sulfated Polysaccharides for Tissue Engineering and Drug Delivery Approaches",
BioMatter, vol. 2, issue 4, pp. 278-289, doi:
doi.org/10.4161/biom.22947, 2012.
Mano J. F., Silva G. A., Azevedo H. S., Malafaya P. B., Sousa R. A., Silva S. S., Boesel L. F., Oliveira J. M., Santos T. C., Marques A. P., Neves N. M., and Reis R. L.,
"Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends",
Journal of the Royal Society Interface , vol. 4, issue 17, pp. 999-1030, 2008.
Invited Review Paper (3)
Silva S. S., Gomes J. M., Rodrigues, L.C., and Reis R. L.,
"Marine-Derived Polymers in Ionic Liquids: Architectures Development and Biomedical Applications.",
Marine Drugs, vol. 18, pp. 346, doi:
10.3390/md18070346, 2020.
Silva S. S., Gomes J. M., Rodrigues, L.C., and Reis R. L.,
"Marine-Derived Polymers in Ionic Liquids: Architectures Development and Biomedical Applications ",
Marine Drugs, vol. 18, issue 7, pp. 346, doi:
10.3390/md18070346, 2020.
Silva T. H., Alves A., Ferreira B. M., Oliveira J. M., Reys L. L., Ferreira R. F., Sousa R. A., Silva S. S., Mano J. F., and Reis R. L.,
"Materials of marine origin: a review on polymers and ceramics of biomedical interest",
International Materials Reviews, vol. 57, issue 5, pp. 276-306, doi:
doi.org/10.1179/1743280412Y.0000000002, 2012.
Invited Lecture (2)
Duarte A. R. C., Santo V. E., Alves A., Silva S. S., Moreira-Silva J., Silva T. H., Marques A. P., Gomes M. E., Sousa R. A., Mano J. F., and Reis R. L.,
"Unleashing the potential of supercritical fluids for polymer processing in tissue engineering and regenerative medicine",
10th International Symposium on Supercritical Fluids, doi:
10.1016/j.supflu.2013.01.004, 2013.
Conference Abstract -ISI Web of Science Indexed (12)
Reys L. L., Silva S. S., Soares da Costa D., Oliveira N. M., Mano J. F., Reis R. L., and Silva T. H.,
"Evaluation of the potential of fucoidan-based microparticles for diabetes treatment",
European Cells & Materials, 1, vol. 1, issue 1, pp. P349, 2016.
Silva T. H., Oliveira C., Reys L. L., Soares da Costa D., Novoa-Carballal R., Oliveira N. M., Ferreira A. S., Nunes C., Silva S. S., Martins A., Coimbra M. A., Mano J. F., Neves N. M., and Reis R. L.,
"Biomedical potential of fucoidan, a seaweed sulfated polysaccharide: from a anticancer agent to a building block of cell encapsulating systems for regenerative medicine",
Front. Bioeng. Biotechnol, pp. 221, doi:
10.3389/conf.FBIOE.2016.01.00221, 2016.
Reys L. L., Silva S. S., Soares da Costa D., Oliveira N. M., Mano J. F., Silva T. H., and Reis R. L.,
"Fucoidan-based Particles for Diabetes Mellitus Treatment.",
Tissue Engineering Parte A, vol. 21, issue S1, pp. A204, doi:
10.1089/ten.tea.2015.5000.abstracts, 2015.
Reys L. L., Silva S. S., Pirraco R. P., Boutinguiza M., Comesana M., Lusquinos F., Pou J., Mano J. F., Silva T. H., and Reis R. L.,
"Biomedical exploitation of squid chitosan using particle aggregation derived composite scaffolds",
Journal of Tissue Engineering and Regenerative Medicine, Supp1, vol. 7, pp. 19, doi:
10.1002/term.1822, 2013.
Silva S. S., Popa E. G., Gomes M. E., Cerqueira M. T., Marques A. P., Caridade S. G., Mano J. F., and Reis R. L.,
"Combination of aloe vera improves the biological performance of chitosan membranes for skin tissue repair",
Journal of Tissue Engineering and Regenerative Medicine, vol. 7, issue s1, pp. 32, doi:
10.1002/term.1822, 2013.
Silva S. S., Popa E. G., Gomes M. E., Oliveira M. B., Mano J. F., and Reis R. L.,
"Designing silk fibroin-based matrices with ionic liquids for tissue engineering strategies using human adipose stem cells",
Journal of Tissue Engineering and Regenerative Medicine, vol. 6, issue Suppl 2, pp. 17, 2012.
Reys L. L., Silva S. S., Boutinguiza S. S., Comesana M., Lusquinos R., Pou J., Mano J. F., Silva T. H., and Reis R. L.,
"Development of marine-based nanocomposite scaffolds for biomedical applications",
3rd Termis World Congress 2012, 2012.
Silva S. S., Duarte A. R. C., Santos T. C., Cerqueira M. T., Marques A. P., Oliveira J. M., Mano J. F., and Reis R. L.,
"Integrated strategy using ionic liquids for the design and processability of natural polymeric architectures for regenerative medicine",
Histology and Histopathology, vol. 26, issue S1, pp. 272, 2011.
Silva S. S., Rodrigues M. T., Motta A., Gomes M. E., Mano J. F., Migliaresi C., and Reis R. L.,
"Novel Genipin Cross-linked Chitosan-Silk based Sponges for the Regeneration and Repair of Cartilage using a Tissue Engineering Approach",
Tissue Engineering: Part A, vol. 14, issue 5, pp. 763, 2008.
Conference Paper -ISI Web of Science Indexed (2)
Comunications - Poster (37)
Silva T. H., Oliveira C., Reys L. L., Soares da Costa D., Novoa-Carballal R., Oliveira N. M., Ferreira A. S., Nunes C., Silva S. S., Martins A., Coimbra M. A., Mano J. F., Neves N. M., and Reis R. L.,
"BIOMEDICAL POTENTIAL OF FUCOIDAN, A SEAWEED SULFATED POLYSACCHARIDE: FROM A ANTICANCER AGENT TO A BUILDING BLOCK OF CELL ENCAPSULATING SYSTEMS FOR REGENERATIVE MEDICINE",
10th World Biomaterials Congress, 2016.
Silva T. H., Barros, A. A., Marques A. L. P., Duarte A. R. C., Diogo G. S., Moreira-Silva J., Reys L. L., Silva S. S., and Reis R. L.,
"The Oceans as a Source and as an Inspiration for Biomaterials Development: Some key examples",
26th Annual Conference – European Society for Biomaterials, 2014.
Reys L. L., Silva S. S., Oliveira J. M., Caridade S. G., Mano J. F., Silva T. H., and Reis R. L.,
"Unraveling the potential of chitosan derived from squid pens for development of structures for tissue
engineering",
1st SPECIAL Open day - Marine Biotechnology,, 2011.
Oliveira J. M., Sousa R. A., Silva S. S., Kotobuki N., Hirose M., Ohgushi H., Mano J. F., and Reis R. L.,
"Surface Engineered Poly(amidoamine) Dendrimer Nanocarriers for Cells and Tissue Engineering Applications",
Annual Tissue Engineering and Regenerative Medicine International Society - TERMIS-NA Meeting, 2010.