Papers in Scientific Journals (35)
Fontelo R., Soares da Costa D., Reis R. L., Novoa-Carballal R., and Pashkuleva I.,
"Bactericidal nanopatterns generated by block copolymer self-assembly",
Acta Biomaterialia, vol. 112, pp. 174-181, doi:
10.1016/j.actbio.2020.06.003, 2020.
Brito A., Abul-Haija Y. M., Soares da Costa D., Novoa-Carballal R., Reis R. L., Ulijn R. V., Pires R. A., and Pashkuleva I.,
"Minimalistic supramolecular proteoglycan mimics by co-assembly of aromatic peptide and carbohydrate amphiphiles",
Chemical Science, vol. 10, pp. 2385 - 2390, doi:
10.1039/c8sc04361b, 2019.
José V. A., Fraguas J., Novoa-Carballal R., Reis R. L., Antelo, Luis T., Pérez-Martín R. I., and Valcarcel J.,
"Isolation and Chemical Characterization of Chondroitin Sulfate from Cartilage By-Products of Blackmouth Catshark (Galeus melastomus)",
Marine Drugs, vol. 16, issue 10, pp. 344, doi:
10.3390/md16070233, 2018.
José V. A., Ramos P., Valcarcel J., Antelo, Luis T., Novoa-Carballal R., Reis R. L., and Pérez Martín R. I.,
"An integral and sustainable valorisation strategy of squid pen by-products",
Journal Of Cleaner Production, vol. 201, pp. 207-218, doi:
10.1016/j.jclepro.2018.07.316, 2018.
Novoa-Carballal R., Carretero A. C., Pacheco R., Reis R. L., and Pashkuleva I.,
"Star-like glycosaminoglycans with superior bioactivity assemble with proteins into microfibers",
Chemistry: A European Journal , vol. 24, pp. 14341 - 14345, doi:
10.1002/chem.201802243, 2018.
Carvalho A. M., Teixeira R., Novoa-Carballal R., Pires R. A., Reis R. L., and Pashkuleva I.,
"Redox-responsive micellar nanoparticles from glycosaminoglycans for CD44 targeted drug delivery",
Biomacromolecules, vol. 19, issue 7, pp. 2991 - 2999, doi:
10.1021/acs.biomac.8b00561, 2018.
José V. A., Noriega D., Ramos P., Valcarcel J., Novoa-Carballal R., Pastrana L., Reis R. L., and Ricardo P. M. I.,
"Optimization of high purity chitin and chitosan production from Illex argentinus pens by a combination of enzymatic and chemical processes",
Carbohydrate Polymers, vol. 174, pp. 262-272, doi:
10.1016/j.carbpol.2017.06.070, 2017.
Silva C., Carretero A. C., Soares da Costa D., Reis R. L., Novoa-Carballal R., and Pashkuleva I.,
"Design of protein delivery systems by mimicking extracellular mechanisms for protection of growth factors",
Acta Biomaterialia, vol. 63, pp. 283 - 293, doi:
10.1016/j.actbio.2017.08.042, 2017.
Valcarcel J., Novoa-Carballal R., Pérez-Martín R. I., Reis R. L., and José V. A.,
"Glycosaminoglycans from marine sources as therapeutic agents",
Biotechnology Advances, vol. 35, issue 6, pp. 711-725, doi:
10.1016/j.biotechadv.2017.07.008, 2017.
Oliveira C., Ferreira A. S., Novoa-Carballal R., Nunes C., Pashkuleva I., Neves N. M., Coimbra M. A., Reis R. L., Martins A., and Silva T. H.,
"The Key Role of Sulfation and Branching on Fucoidan Antitumor Activity",
Macromolecular Bioscience, vol. 17, issue 5, pp. 1600340, doi:
10.1002/mabi.201600340, 2017.
Novoa-Carballal R., Pérez-Martín, R.; Blanco S. M.;, Nunes C., Coimbra M. A., Silva T. H., Reis R. L., and José V. A.,
"By-products of Scyliorhinus canicula, Prionace glauca and Raja clavata: A valuable source of predominantly 6S sulfated chondroitin sulfate",
Carbohydrate Polymers, vol. 157, pp. 31-38, doi:
10.1016/j.carbpol.2016.09.050, 2017.
da Silva L. P., Pirraco R. P., Santos T. C., Novoa-Carballal R., Cerqueira M. T., Reis R. L., Correlo V. M., and Marques A. P.,
"Neovascularization Induced by the Hyaluronic Acid-Based Spongy-Like Hydrogels Degradation Products",
ACS Applied Materials and Interfaces, doi:
10.1021/acsami.6b11684, 2016.
Pires R. A., Abul-Haija Y. M., Soares da Costa D., Novoa-Carballal R., Reis R. L., Ulijn R. V., and Pashkuleva I.,
"Controlling Cancer Cell Fate Using Localized Biocatalytic Self-Assembly of an Aromatic Carbohydrate Amphiphile",
Journal of the American Chemical Society, vol. 137, issue 2, pp. 576-579, doi:
10.1021/ja5111893, 2015.
Ozturk K., Fernandez-Megia E., Novoa-Carballal R., Riguera R., Yemisci M., Gurny R., Dalkara T., Couvreur P., and Capan Y.,
"Comparative in vitro studies on PBN loaded nanoparticles prepared by biodegradable chitosan, PLGA polymers and their PEGylated block copolymers.",
J. Drug. Del.. Sci. Tech., vol. 24, issue 2, pp. 148, 2014.
Novoa-Carballal R., Silva C., Moller S., Schnabelrauch M., Reis R. L., and Pashkuleva I.,
"Tunable nano-carriers from clicked glycosaminoglycan block copolymers",
Journal of Materials Chemistry B, vol. 2, issue 26, pp. 4177-4184, doi:
10.1039/C4TB00410H, 2014.
Torrecilla D., Lozano M. V., Lallana E., Neissa J. I., Novoa-Carballal R., Vidal A., Fernandez-Megia E., Torres D., Riguera R., Alonso M., and Dominguez F.,
"Anti-tumor efficacy of chitosan-g-poly(ethylene glycol) nanocapsules containing docetaxel: Anti-TMEFF-2 functionalized nanocapsules vs. non-functionalized nanocapsules",
European Journal of Pharmaceutics and Biopharmaceutics, vol. 83, pp. 330, 2013.
Jakob F., Pfaff A., Novoa-Carballal R., Rübsam H., Becker T., and Vogel R. F.,
"Structural and functional characterization of fructans produced by acetic acid bacteria",
Carbohydrate Polymers, vol. 92, pp. 1234, 2013.
Raviña M., Cubillo E., Olmeda D., Novoa-Carballal R., Novoa-Carballal R., Fernandez-Megia E., Riguera R., Sanchez A., Cano A., and Alonso M.,
"Hyaluronic Acid/Chitosan-g-Poly(ethylene glycol) Nanoparticles for Gene Therapy: An Application for pDNA and siRNA Delivery",
Pharmaceutical Research, vol. 27, pp. 2544, 2010.
O. P., Atkas Y., T. D., Alonso M., Fernandez-Megia E., Novoa-Carballal R., Riguera R., P. C., and Y. C.,
"Preparation and evaluation of alpha-phenyl-n-tert-butyl nitrone (PBN)-encapsulated chitosan and PEGylated chitosan nanoparticles",
Die Pharmazie, vol. 29, pp. 13761, 2009.
Karatas. H., Aktas Y., Gursoy-Ozdemir Y., Bodur E., Yemisci M., Caba S., Vural A., Pinarbasli O., Capan Y., Fernandez-Megia E., Novoa-Carballal R., Riguera R., Andrieux P., Couvreur P., and Dalkara T.,
"A Nanomedicine Transports a Peptide Caspase-3 Inhibitor across the Blood–Brain Barrier and Provides Neuroprotection",
The Journal of Neuroscience, issue 29, pp. 13761, 2009.
Noemi C., Magnus K. - H., Novoa-Carballal R., Fernandez-Megia E., Riguera R., and Alonso M.,
"Ionically Crosslinked Chitosan Nanoparticles as Gene Delivery Systems: Effect of PEGylation Degree on In Vitro and In Vivo Gene Transfer",
Journal of Biomedical Nanotechnology, vol. 5, pp. 162, 2009.
Prego C., Torres D., Fernandez-Megia E., Novoa-Carballal R., Emilio Q., and Alonso M.,
"Chitosan-PEG Nanocapsules as New Carriers for Oral Peptide Delivery",
Journal of the Controlled Release Society, vol. 11, pp. 299, 2006.
Aktas Y., Yemisci, M., Andrieux K., Gursoy-Ozdemir Y., Alonso M., Fernandez-Megia E., Novoa-Carballal R., Quiñoa E., Riguera R., Sargon M. F., Çelik H., Demir H., Hıncal A. S., Dalkara T., Y., Capan Y., and Couvreur P.,
"Development and Brain Delivery of Chitosan-PEG Nanoparticles Functionalized with the Monoclonal Antibody OX26",
Bioconjugate Chemistry, vol. 16, pp. 1503, 2005.
Review Paper (1)
Book Chapter (1)
Conference Abstract -ISI Web of Science Indexed (3)
Brito A., Abul-Haija Y. M., Soares da Costa D., Novoa-Carballal R., Reis R. L., Ulijn R. V., Pires R. A., and Pashkuleva I.,
"Co-assembly of peptide and carbohydrate amphiphiles to generate proteoglycan mimics",
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, vol. 256, pp. 113-CARB, 2018.
Silva T. H., Oliveira C., Reys L. L., Soares da Costa D., Novoa-Carballal R., Oliveira N. M., Ferreira A. S., Nunes C., Silva S. S., Martins A., Coimbra M. A., Mano J. F., Neves N. M., and Reis R. L.,
"Biomedical potential of fucoidan, a seaweed sulfated polysaccharide: from a anticancer agent to a building block of cell encapsulating systems for regenerative medicine",
Front. Bioeng. Biotechnol, pp. 221, doi:
10.3389/conf.FBIOE.2016.01.00221, 2016.
Comunications - Poster (7)
Brito A., Soares da Costa D., Novoa-Carballal R., Abul-Haija Y. M., Reis R. L., Ulijn R. V., Pires R. A., and Pashkuleva I.,
"Biofunctional supramolecular hydrogels by co-assembly of simple carbohydrate and peptide amphiphiles",
TERMIS, 2017.
Silva T. H., Oliveira C., Reys L. L., Soares da Costa D., Novoa-Carballal R., Oliveira N. M., Ferreira A. S., Nunes C., Silva S. S., Martins A., Coimbra M. A., Mano J. F., Neves N. M., and Reis R. L.,
"BIOMEDICAL POTENTIAL OF FUCOIDAN, A SEAWEED SULFATED POLYSACCHARIDE: FROM A ANTICANCER AGENT TO A BUILDING BLOCK OF CELL ENCAPSULATING SYSTEMS FOR REGENERATIVE MEDICINE",
10th World Biomaterials Congress, 2016.
Comunication - Oral (8)
Brito A., Soares da Costa D., Novoa-Carballal R., Abul-Haija Y. M., Reis R. L., Ulijn R. V., Pires R. A., and Pashkuleva I.,
"Supramolecular hydrogels based on the co-assembly of simple carbohydrates and peptide amphiphiles for biological applications",
12ª Reunião do Grupo de Glúcidos, 2017.
da Silva L. P., Pirraco R. P., Santos T. C., Novoa-Carballal R., Cerqueira M. T., Reis R. L., Correlo V. M., and Marques A. P.,
"Hyaluronidase‐mediated degradation products of hyaluronic acid‐based spongylike hydrogels promote neovascularization",
Chem2Nature Conference, 2016.
Patent (1)