Biomaterials, Biodegradables and Biomimetics Research Group

Book Chapter

Silk Fibroin-Based Scaffold for Bone Tissue Engineering

Abstract

Regeneration of diseased or damaged skeletal tissues is one of the challenge that needs to be
solved. Although there have been many bone tissue engineering developed, scaffold-based
tissue engineering complement the conventional treatment for large bone by completing
biological and functional environment. Among many materials, silk fibroin (SF) is one of the favorable material for applications in bone tissue engineering scaffolding. SF is a fibrous protein mainly extracted from Bombyx
mori. and spiders. SF has been used as a biomaterial for bone graft by its unique mechanical properties, controllable biodegradation rate and high biocompatibility. Moreover, SF can be processed using conventional and advanced biofabrication methods to form various scaffold types such as sponges, mats,
hydrogels and films. This review discusses about recent application and advancement of SF as a biomaterial.

Journal
Silk Fibroin-Based Scaffold for Bone Tissue Engineering
Publisher
Springer Nature
URL
https://doi.org/10.1007/978-981-13-0947-2_20
Keywords
bone, silk, Tissue engineering
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
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