Biomaterials, Biodegradables and Biomimetics Research Group

Conference Abstract -ISI Web of Science Indexed

Oxygen conditioning effect on an in vitro co-culture model of tendon-to-bone interface

Abstract

Tendon-to-bone interface comprises a heterotypic cellular niche. The native interface is hypovascular, suggesting that the junction is physiologically hypoxic. As it bridges tendon and bone, which require different oxygen concentrations, a tight coordination of different oxygen concentrations along the junction must be considered when trying to mimic and understand biological events occurring within the tissue. Herein, an optimized in vitro co-culture model of tendon-derived cells (hTDCs) and pre-osteoblasts (pre-OBs) [1] was used to study the effect of a restricted oxygen environment on cell behavior.

Journal
European Cells & Materials Conferences
ISSN
123
URL
https://www.ecmconferences.org/abstracts/2019/Collection3/c3.html
Keywords
co-culture models, hypoxia
Rights
Open Access
Peer Reviewed
Yes
Status
published
Project
MagTT
Year of Publication
2019
Date Published
2019-09-01
Search Google ScholarGenerate BibTexDownload RTF
This website uses cookies. By using this website you consent to our use of these cookies. For more information visit our Policy Page.