Biochemical gradients to form a 3-D osteochondral in vitro model

last updated: 2020-01-31
ProjectHierarchiTech :: publications list
TitleBiochemical gradients to form a 3-D osteochondral in vitro model
Publication TypeComunication - Oral
Year of Publication2019
AuthorsCanadas R. F., Ren T., Marques A. P., Oliveira J. M., Reis R. L., and Demirci U.

Gradients of 3-D complex functional patterns at micro-scale are common in nature [1]. While diverse fabrication techniques based on material science, micro-scale engineering, and microfluidics have been used to synthesize biomimetic and tailored microenvironments [2,3], a great need is still present for improved methods of gradient tissue engineering. Here, we developed the precise spatial control over both cell/tissue phenotype and pre-vasculature formation, which opens-up possibilities for the study of complex tissues interfaces, with broader applications in drug testing and regenerative medicine.

Conference NameTERMIS-EU 2019
Date Published2019-05-30
Conference LocationRhodes, Greece
Keywords3D, bioreactor, In Vitro Model, Osteochondral
Peer reviewedyes

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