Biomaterials, Biodegradables and Biomimetics Research Group

Abstract

Tendon stem cells constitute a heterogeneous population of stem and progenitor cells that is involved in tendon formation and healing. The basic understanding of the interactions between tendon cells and their surroundings can enable the development of improved regenerative therapies. In this chapter, the main characteristics of their microenvironment – niche – are reviewed. In particular, the importance of signaling molecules and extracellular matrix (ECM) are highlighted, focusing on their potential role in tendon regeneration. 

Journal
Tissue-Specific Stem Cell Niche
Pagination
221-244
Publisher
Springer Publisher
ISSN
2196-8985
ISBN
978-3-319-21704-8
URL
http://link.springer.com/chapter/10.1007/978-3-319-21705-5_10
Keywords
Cell therapy, Extracellular matrix, Niche, regenerative medicine, Tendon healing/repair, Tendon stem/progenitor cells, Tenogenesis
Rights
Restricted Access
Peer Reviewed
Yes
Status
published
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