Biomaterials, Biodegradables and Biomimetics Research Group

Conference Abstract -ISI Web of Science Indexed

Functional chitosan microcarriers for selective cell attachment and expansion

Abstract

The success of many stem cell applications in the biomedical field is highly dependent on the development of reliable techniques either for isolation or selection of specific cell populations with a very high yield and purity.1 In this work we propose the use of chitosan microparticles (μPs) to capture a specific cell type based in the concept of antibody-antigen binding. Our goal was to create new biomaterials capable of selecting within a heterotypic cell suspension, a specific sub-population, and supporting subsequent cell expansion. Such system simultaneously allows the selection and acts as a microcarrier for a specific target, thus reducing cell manipulation and time-consumption.

Journal
Journal of Tissue Engineering and Regenerative Medicine
Volume
8
Pagination
160-161
Publisher
WILEY-VCH Verlag GmbH & Co.
Keywords
cell expansion, cell separation, microcarriers
Rights
Open Access
Peer Reviewed
Yes
Status
published
Year of Publication
2014
Date Published
2014-06-10
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